Brain Organoids for Neurophysiology Inferences

12th September 2024

Timing : 1 pm EST

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Brain organoids, derived from human stem cells, exhibit a repertoire of features that may serve as a heuristic tool for neurophysiologic insights. These tiny structures have a three dimensional architecture and differentiate into a very broad variety neuronal and glial cell types. Remarkably, they also display electrophysiological features with a temporal structure that bears some resemblance to encoding patterns in the brain. Because organoid activity arises spontaneously the putative encoding patterns we observe represent a pre-configured state achieved in the absence of any experience.