32.

Abshire JR, Rowlands CJ, Ganesan SM, So PT, Niles JC. Quantification of labile heme in live malaria parasites using a genetically encoded biosensor; Proc Natl Acad Sci U S A; 2017 114(11):E2068-E2076. [PMID: 28242687 ]

31.

Spillman NJ, Beck JR, Ganesan SM, Niles JC, Goldberg DE. The chaperonin TRiC forms an oligomeric complex in the malaria parasite cytosol; Cell Microbiol; 2017 19(6). [PMID: 28067475 ]

30.

Sidik SM, Huet D, Ganesan SM, Huynh MH, Wang T, Nasamu AS, Thiru P, Saeij JP, Carruthers VB, Niles JC, Lourido S. A genome-wide CRISPR screen in Toxoplasma identifies essential Apicomplexan genes; Cell; 2016 166(6):1423-1435.e12. [PMID: 27594426 ]

29.

Dankwa S, Lim C, Bei AK, Jiang RH, Abshire JR, Patel SD, Goldberg JM, Moreno Y, Kono M, Niles JC, Duraisingh MT. Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite; Nat Commun; 2016 7:11187. [PMID: 27041489 ]

28.

Ganesan SM, Falla A, Goldfless SJ, Nasamu AS, Niles JC. Synthetic RNA-protein modules integrated with native translation mechanisms to control gene expression in malaria parasites; Nat Commun; 2016 7:10727. [PMID: 26925876 ]

27.

Birch CM, Hou HW, Han J, Niles JC. Identification of malaria parasite-infected red blood cell surface aptamers by inertial microfluidic SELEX (I-SELEX); Sci Rep; 2015 5:11347. [PMID: 26126714 ]

26.

Goldfless SJ, Wagner JC, Niles JC. Versatile control of Plasmodium falciparum gene expression with an inducible protein-RNA interaction; Nat Commun; 2014 5:5329. [PMID: 25370483]

25.

Wagner JC, Platt RJ, Goldfless SJ, Zhang F, Niles JC. Efficient CRISPR-Cas9-mediated genome editing in Plasmodium falciparum; Nat Methods; 2014 11(9):915-8. [PMID: 25108687]

24.

Wagner JC, Goldfless SJ, Ganesan SM, Lee MC, Fidock DA, Niles JC. An integrated strategy for efficient vector construction and multi-gene expression in Plasmodium falciparum; Malar J; 2013 12:373. [PMID: 24160265 ]

23.

Belmont, B.J. and Niles, J.C.; Inducible control of subcellular RNA localization using a synthetic protein-RNA aptamer interaction; PLOS ONE; 2012 7(10):e46868. [PMID: 23056498]

22.

Zhao, W., Dauwels, J., Niles, J.C. and Cao, J; Computational synchronization of microarray data with application to Plasmodium falciparum; Proteome Science; 2012; 10 Suppl 1:S10. [PMID: 22759568]

21.

Niles, J.C.; Malarial parasites accumulate labile zinc pools; Chemistry and Biology; 2012; 19(6):660-661. [PMID: 22726676]

20.

Goldfless, S.J.*, Belmont, B.J.*, Liu, J.F., de Paz, A.M. and Niles, J.C.; Direct and specific chemical control of eukaryotic translation with a synthetic RNA-protein interaction; Nucleic Acids Research; 2012; 40(9):e64. * = Equal contribution. [PMID: 22275521]

19.

Kang, J.W., Lue, N., Kong, C.R., Barman, I., Dingari, N.C., Goldfless, S.J., Niles, J.C., Dasari, R.R., Feld M.S.; Combined confocal Raman and quantitative phase microscopy system for biomedical diagnosis; Biomedical Optics Express; 2011; 2(9):2484-2492. [PMID: 21991542]

18.

Bow, H., Pivkin I.V., Diez-Silva, M., Goldfless, S.J., Dao, M., Niles J.C., Suresh, S. and Han, J.; A microfabricated deformability-based flow cytometer with application to malaria; Lab on a Chip; 2011; 11(6), 1065-1073. [PMID: 21293801]

17.

Belmont, B.J. and Niles, J.C.; Engineering a direct and inducible protein-RNA interaction to regulate RNA biology; ACS Chemical Biology; 2010; 5(9), 851-861. [PMID: 20545348]

16.

Niles, J.C., DeRisi, J.L. and Marletta, M.A.; Inhibiting Plasmodium falciparum growth and heme detoxification pathway using heme-binding DNA aptamers; Proceedings of the National Academy of Sciences USA; 2009; 106(32), 13266-13271. [PMID: 19633187]

15.

Niles, J.C. and Marletta, M.A.; Utilizing RNA aptamers to probe a physiologically important heme–regulated cellular network; 2006; ACS Chemical Biology; 1(8), 515–524. [PMID: 17168539]

14.

Niles, J.C., Wishnok, J.S. and Tannenbaum, S.R.; Peroxynitrite–induced oxidation and nitration products of guanine and 8–oxoguanine: Structures and mechanisms of product formation; Nitric Oxide; 2006; 14, 109–121. [PMID: 16352449]

13.

Henderson, P.T., Neeley, W.L., Delaney, J.C., Gu, F., Niles, J.C., Tannenbaum, S.R., and Essigmann, J.M.; Urea lesion formation in DNA produced by 7,8–dihydro–8–oxoguanine oxidation and hydrolysis: a novel pathway to a potent source of point mutations; Chemical Research in Toxicology; 2005; 18(1), 12–18. [PMID: 15651843]

12.

Niles, J.C., Wishnok, J.S., and Tannenbaum, S.R.; Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8–oxoguanosine oxidation at low fluxes of peroxynitrite: Mechanistic studies with ¹⁸O; Chemical Research in Toxicology; 2004: 17(11), 1510–1519. [PMID: 15540949]

11.

Niles, J.C., Wishnok, J.S., and Tannenbaum, S.R.; Mass Spectrometric identification of 4–hydroxy–2,5–dioxo–imidazolidine–4–carboxylic acid during oxidation of 8–oxoguanosine by peroxynitrite and KHSO₅/CoCl₂; Chemical Research in Toxicology; 2004: 17(11), 1501–1509. [PMID: 15540948]

10.

Yu, H, Niles, J.C., Wishnok, J.S., and Tannenbaum, S.R.; Spirodihydantoin is a minor product of 5–hydroxyisourate in urate oxidation; Organic Letters; 2004: 6(19), 3417–3420. [PMID: 15355066]

9.

Lee, J.M., Niles, J.C., Wishnok, J.S. and Tannenbaum, S.R.; Peroxynitrite reacts with 8–nitropurines to yield 8–oxopurines; Chemical Research in Toxicology; 2002; 15(1), 7–14. [PMID: 11800591]

8.

Niles, J.C., Wishnok, J.S., and Tannenbaum, S.R.; A novel nitroimidazole compound formed during the reaction of peroxynitrite with 2',3',5'–tri–O–acetyl–guanosine; Journal of the American Chemical Society; 2001; 123(49), 12147–12151. [PMID: 11734012]

7.

Niles, J.C., Wishnok, J.S., and Tannenbaum, S.R.; Spiroiminodihydantoin is the major product of the 8–oxo–7,8–dihydroguanosine reaction with peroxynitrite in the presence of thiols and guanosine photooxidation by methylene blue; Organic Letters; 2001; 3(7), 963–966. [PMID: 11277770]

6.

Niles, J.C., Wishnok, J.S., and Tannenbaum, S.R.; A novel nitration product formed during the reaction of peroxynitrite with 2,3,5–tri–O–acetyl–8–oxoguanosine: N–nitro,N'–[1–(2,3,5–tri–O–acetyl–β–D–erythro–pentofuranosyl)–2,4–dioxo–imidazolidin–5–ylidene]guanidine, Chemical Research in Toxicology; 2000; 13(5), 390–396. [PMID: 10813656]

5.

Niles, J.C., Burney, S., Singh, S.P., Wishnok, J.S., and Tannenbaum, S.R.; Peroxynitrite reaction products of 3',5'–di–O–acetyl–8–oxo–2'–deoxyguanosine; Proceedings of the National Academy of Sciences, USA; 1999; 96(21), 11729–11734. [PMID: 10518518]

4.

Burney, S, Niles, J.C., Wishnok, J.S., Dedon, P.C. and Tannenbaum, S.R.; DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite; Chemical Research in Toxicology; 1999; 12(6), 513–520. [PMID: 10368314]

3.

Tretyakova, N. Yu, Niles, J.C., Burney, S., Wishnok, J.S. and Tannenbaum, S.R.; Peroxynitrite–induced reactions of synthetic oligonucleotides containing 8–oxoguanine; Chemical Research in Toxicology; 1999; 12(5), 459–466. [PMID: 10328757]

2.

Burney, S., Caulfield, J.L., Niles, J.C., Wishnok, J.S. and Tannenbaum, S.R.; The chemistry of DNA damage from nitric oxide and peroxynitrite; Mutation Research; 1999; 424, 37–49. [PMID: 10064848]

1.

Butt, J.N., Niles, J, Armstrong, F.A., Breton, J. and Thomson, A.J.; Formation and properties of a stable "high potential" copper–iron–sulphur cluster in ferredoxin; Nature Structure Biology; 1994; 1(7), 427–432. [PMID: 7664060]